ihc 91882 cst cd8 Search Results


96
Cell Signaling Technology Inc anticd86 mab
Anticd86 Mab, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/CD86+Rabbit+mAb/pm41360425-81-44-47
Average 96 stars, based on 1 article reviews
anticd86 mab - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier

96
Cell Signaling Technology Inc anti cd8
Anti Cd8, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/CD8alpha+Rabbit+mAb/pm40679093-310-15-21
Average 96 stars, based on 1 article reviews
anti cd8 - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier

96
Cell Signaling Technology Inc blocking solution
Blocking Solution, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/Immunofluorescence+Blocking+Buffer/pm37516825-454-5-20
Average 96 stars, based on 1 article reviews
blocking solution - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier

94
Santa Cruz Biotechnology anti pstat1
Anti Pstat1, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 94/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/p-Stat1+Antibody/pm37516825-454-35-36
Average 94 stars, based on 1 article reviews
anti pstat1 - by Bioz Stars, 2026-09
94/100 stars
  Buy from Supplier

96
Cell Signaling Technology Inc anti cd68
Anti Cd68, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 96/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/CD68+XP+Rabbit+mAb/pmc11560440-67-6-9
Average 96 stars, based on 1 article reviews
anti cd68 - by Bioz Stars, 2026-09
96/100 stars
  Buy from Supplier

95
Cell Signaling Technology Inc cd20
FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, CD68+, <t>CD20+,</t> CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages (CD68+, yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).
Cd20, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/CD20+XP+Rabbit+mAb/pm37162299-44-23-25
Average 95 stars, based on 1 article reviews
cd20 - by Bioz Stars, 2026-09
95/100 stars
  Buy from Supplier

95
Cell Signaling Technology Inc adar1
FIGURE 1 Excessive expression of adenosine deaminase RNA-specific 1 <t>(ADAR1)</t> contributes to poor prognosis in non-small cell lung cancer (NSCLC). (A) Representative images of IHC staining with an ADAR1 antibody on lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC) tumor tissues and their adjacent normal lung tissues. Scale bars: 200 μm. (B) Proportion of ADAR1high and ADAR1low cases of LUAD or LUSC. (C) ADAR1 mRNA expression levels in NSCLC, LUAD, and LUSC (***p < 0.001). (D) Overall survival curves based on ADAR1 mRNA expression in patients with NSCLC, LUSC, or LUAD.
Adar1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 95/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/ADAR1+XP+Rabbit+mAb/pm37162299-44-4-6
Average 95 stars, based on 1 article reviews
adar1 - by Bioz Stars, 2026-09
95/100 stars
  Buy from Supplier

97
Cell Signaling Technology Inc anti arg1
FIGURE 1 Excessive expression of adenosine deaminase RNA-specific 1 <t>(ADAR1)</t> contributes to poor prognosis in non-small cell lung cancer (NSCLC). (A) Representative images of IHC staining with an ADAR1 antibody on lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC) tumor tissues and their adjacent normal lung tissues. Scale bars: 200 μm. (B) Proportion of ADAR1high and ADAR1low cases of LUAD or LUSC. (C) ADAR1 mRNA expression levels in NSCLC, LUAD, and LUSC (***p < 0.001). (D) Overall survival curves based on ADAR1 mRNA expression in patients with NSCLC, LUSC, or LUAD.
Anti Arg1, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/Arginase-1+XP+Rabbit+mAb/pmc10386714-532-46-47
Average 97 stars, based on 1 article reviews
anti arg1 - by Bioz Stars, 2026-09
97/100 stars
  Buy from Supplier

97
Cell Signaling Technology Inc cd68
FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, <t>CD68+,</t> CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages <t>(CD68+,</t> yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).
Cd68, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 97/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/CD68+Rabbit+mAb/pm37162299-44-12-14
Average 97 stars, based on 1 article reviews
cd68 - by Bioz Stars, 2026-09
97/100 stars
  Buy from Supplier

98
Cell Signaling Technology Inc anti cd206
FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, <t>CD68+,</t> CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages <t>(CD68+,</t> yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).
Anti Cd206, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 98/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/CD206%2FMRC1+XP+Rabbit+mAb/pm41606294-48-36-37
Average 98 stars, based on 1 article reviews
anti cd206 - by Bioz Stars, 2026-09
98/100 stars
  Buy from Supplier

99
Cell Signaling Technology Inc anti cleaved casp3
FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, <t>CD68+,</t> CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages <t>(CD68+,</t> yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).
Anti Cleaved Casp3, supplied by Cell Signaling Technology Inc, used in various techniques. Bioz Stars score: 99/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ihc+91882+cst+cd8/Cleaved+Caspase-3+(Asp175)+Antibody/pmc10386714-532-30-32
Average 99 stars, based on 1 article reviews
anti cleaved casp3 - by Bioz Stars, 2026-09
99/100 stars
  Buy from Supplier

Image Search Results


FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, CD68+, CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages (CD68+, yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).

Journal: Cancer medicine

Article Title: ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.

doi: 10.1002/cam4.6044

Figure Lengend Snippet: FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, CD68+, CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages (CD68+, yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).

Article Snippet: After sequential application of ADAR1 (#81284, Cell Signaling Technology), CD4 (ab183685, Abcam), CD68 (#97778, Cell Signaling Technology) and CD8 (ab237709, Abcam) antibodies or CD20 (#48750, Cell Signaling Technology), CD84 (ab131256, Abcam), CD86 (#91882, Cell Signaling Technology), and CD206 (#24595, Cell Signaling Technology) antibodies to the sections, horseradish peroxidase- conjugated secondary antibody incubation nloaded from https://onlinelibrary.w iley.com /doi/10.1002/cam 4.6044 by G itam U niversity, W iley O nline L ibrary on [29/01/2024].

Techniques: Multiplex Assay, Immunohistochemistry, Staining, Derivative Assay

FIGURE 1 Excessive expression of adenosine deaminase RNA-specific 1 (ADAR1) contributes to poor prognosis in non-small cell lung cancer (NSCLC). (A) Representative images of IHC staining with an ADAR1 antibody on lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC) tumor tissues and their adjacent normal lung tissues. Scale bars: 200 μm. (B) Proportion of ADAR1high and ADAR1low cases of LUAD or LUSC. (C) ADAR1 mRNA expression levels in NSCLC, LUAD, and LUSC (***p < 0.001). (D) Overall survival curves based on ADAR1 mRNA expression in patients with NSCLC, LUSC, or LUAD.

Journal: Cancer medicine

Article Title: ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.

doi: 10.1002/cam4.6044

Figure Lengend Snippet: FIGURE 1 Excessive expression of adenosine deaminase RNA-specific 1 (ADAR1) contributes to poor prognosis in non-small cell lung cancer (NSCLC). (A) Representative images of IHC staining with an ADAR1 antibody on lung adenocarcinoma (LUAD) and lung squamous carcinoma (LUSC) tumor tissues and their adjacent normal lung tissues. Scale bars: 200 μm. (B) Proportion of ADAR1high and ADAR1low cases of LUAD or LUSC. (C) ADAR1 mRNA expression levels in NSCLC, LUAD, and LUSC (***p < 0.001). (D) Overall survival curves based on ADAR1 mRNA expression in patients with NSCLC, LUSC, or LUAD.

Article Snippet: After sequential application of ADAR1 (#81284, Cell Signaling Technology), CD4 (ab183685, Abcam), CD68 (#97778, Cell Signaling Technology) and CD8 (ab237709, Abcam) antibodies or CD20 (#48750, Cell Signaling Technology), CD84 (ab131256, Abcam), CD86 (#91882, Cell Signaling Technology), and CD206 (#24595, Cell Signaling Technology) antibodies to the sections, horseradish peroxidase- conjugated secondary antibody incubation nloaded from https://onlinelibrary.w iley.com /doi/10.1002/cam 4.6044 by G itam U niversity, W iley O nline L ibrary on [29/01/2024].

Techniques: Expressing, Immunohistochemistry

FIGURE 2 Adenosine deaminase RNA-specific 1 (ADAR1) expression is associated with the clinicopathological characteristics and prognosis of patients with lung adenocarcinoma (LUAD). (A) Analysis of ADAR1 expression levels based on the clinical stages of The Cancer Genome Atlas-LUAD. (B) The expression levels of ADAR1 in stage I, stage II, stage III, stage IV, and normal tissues of patients with LUAD from the present cohort (n = 100). (C) Immunoreactivity score of ADAR1 expression in patients with LUAD at different stages. (D) K-M survival analysis of overall survival for LUAD patients according to the level of ADAR1 protein expression. (E) Univariate and (F) multivariate Cox analyses of ADAR1 in LUAD patients. (***p < 0.001, **p < 0.01, ns p > 0.5 nonsignificant).

Journal: Cancer medicine

Article Title: ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.

doi: 10.1002/cam4.6044

Figure Lengend Snippet: FIGURE 2 Adenosine deaminase RNA-specific 1 (ADAR1) expression is associated with the clinicopathological characteristics and prognosis of patients with lung adenocarcinoma (LUAD). (A) Analysis of ADAR1 expression levels based on the clinical stages of The Cancer Genome Atlas-LUAD. (B) The expression levels of ADAR1 in stage I, stage II, stage III, stage IV, and normal tissues of patients with LUAD from the present cohort (n = 100). (C) Immunoreactivity score of ADAR1 expression in patients with LUAD at different stages. (D) K-M survival analysis of overall survival for LUAD patients according to the level of ADAR1 protein expression. (E) Univariate and (F) multivariate Cox analyses of ADAR1 in LUAD patients. (***p < 0.001, **p < 0.01, ns p > 0.5 nonsignificant).

Article Snippet: After sequential application of ADAR1 (#81284, Cell Signaling Technology), CD4 (ab183685, Abcam), CD68 (#97778, Cell Signaling Technology) and CD8 (ab237709, Abcam) antibodies or CD20 (#48750, Cell Signaling Technology), CD84 (ab131256, Abcam), CD86 (#91882, Cell Signaling Technology), and CD206 (#24595, Cell Signaling Technology) antibodies to the sections, horseradish peroxidase- conjugated secondary antibody incubation nloaded from https://onlinelibrary.w iley.com /doi/10.1002/cam 4.6044 by G itam U niversity, W iley O nline L ibrary on [29/01/2024].

Techniques: Expressing

FIGURE 3 Elevated adenosine deaminase RNA-specific 1 (ADAR1) expression is associated with lymph node metastasis (LNM) in lung adenocarcinoma (LUAD). ADAR1 expression level in LUAD with or without LNM (A) and their immunoreactive scores (B). Scale bars: 100 μm. ADAR1 expression level in primary LUAD or paired LNM lesions (C) and their immunoreactive scores (D). (mean ± SD, Student's t-test, **p < 0.01, *p < 0.05).

Journal: Cancer medicine

Article Title: ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.

doi: 10.1002/cam4.6044

Figure Lengend Snippet: FIGURE 3 Elevated adenosine deaminase RNA-specific 1 (ADAR1) expression is associated with lymph node metastasis (LNM) in lung adenocarcinoma (LUAD). ADAR1 expression level in LUAD with or without LNM (A) and their immunoreactive scores (B). Scale bars: 100 μm. ADAR1 expression level in primary LUAD or paired LNM lesions (C) and their immunoreactive scores (D). (mean ± SD, Student's t-test, **p < 0.01, *p < 0.05).

Article Snippet: After sequential application of ADAR1 (#81284, Cell Signaling Technology), CD4 (ab183685, Abcam), CD68 (#97778, Cell Signaling Technology) and CD8 (ab237709, Abcam) antibodies or CD20 (#48750, Cell Signaling Technology), CD84 (ab131256, Abcam), CD86 (#91882, Cell Signaling Technology), and CD206 (#24595, Cell Signaling Technology) antibodies to the sections, horseradish peroxidase- conjugated secondary antibody incubation nloaded from https://onlinelibrary.w iley.com /doi/10.1002/cam 4.6044 by G itam U niversity, W iley O nline L ibrary on [29/01/2024].

Techniques: Expressing

FIGURE 4 Correlation of adenosine deaminase RNA-specific 1 (ADAR1) with tumor immune infiltration in lung adenocarcinoma (LUAD). Correlation between ADAR1 and 22 tumor-infiltrating immune cells in LUAD samples as analyzed via cell-type identification by estimating relative subsets of known RNA transcripts. An absolute value of |Rho| > 0.1 and p < 0.05 implied that the ADAR1 expression level was significantly associated with the number of immune cells.

Journal: Cancer medicine

Article Title: ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.

doi: 10.1002/cam4.6044

Figure Lengend Snippet: FIGURE 4 Correlation of adenosine deaminase RNA-specific 1 (ADAR1) with tumor immune infiltration in lung adenocarcinoma (LUAD). Correlation between ADAR1 and 22 tumor-infiltrating immune cells in LUAD samples as analyzed via cell-type identification by estimating relative subsets of known RNA transcripts. An absolute value of |Rho| > 0.1 and p < 0.05 implied that the ADAR1 expression level was significantly associated with the number of immune cells.

Article Snippet: After sequential application of ADAR1 (#81284, Cell Signaling Technology), CD4 (ab183685, Abcam), CD68 (#97778, Cell Signaling Technology) and CD8 (ab237709, Abcam) antibodies or CD20 (#48750, Cell Signaling Technology), CD84 (ab131256, Abcam), CD86 (#91882, Cell Signaling Technology), and CD206 (#24595, Cell Signaling Technology) antibodies to the sections, horseradish peroxidase- conjugated secondary antibody incubation nloaded from https://onlinelibrary.w iley.com /doi/10.1002/cam 4.6044 by G itam U niversity, W iley O nline L ibrary on [29/01/2024].

Techniques: Expressing

FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, CD68+, CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages (CD68+, yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).

Journal: Cancer medicine

Article Title: ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.

doi: 10.1002/cam4.6044

Figure Lengend Snippet: FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, CD68+, CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages (CD68+, yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).

Article Snippet: After sequential application of ADAR1 (#81284, Cell Signaling Technology), CD4 (ab183685, Abcam), CD68 (#97778, Cell Signaling Technology) and CD8 (ab237709, Abcam) antibodies or CD20 (#48750, Cell Signaling Technology), CD84 (ab131256, Abcam), CD86 (#91882, Cell Signaling Technology), and CD206 (#24595, Cell Signaling Technology) antibodies to the sections, horseradish peroxidase- conjugated secondary antibody incubation nloaded from https://onlinelibrary.w iley.com /doi/10.1002/cam 4.6044 by G itam U niversity, W iley O nline L ibrary on [29/01/2024].

Techniques: Multiplex Assay, Immunohistochemistry, Staining, Derivative Assay

FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, CD68+, CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages (CD68+, yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).

Journal: Cancer medicine

Article Title: ADAR1 is a prognostic biomarker and is correlated with immune infiltration in lung adenocarcinoma.

doi: 10.1002/cam4.6044

Figure Lengend Snippet: FIGURE 5 Adenosine deaminase RNA-specific 1 (ADAR1) is involved in immune cell infiltration in lung adenocarcinoma (LUAD) tissue. (A) Multiplex immunohistochemistry staining of LUAD sections of the high- (upper panel) or low- (lower panel) ADAR1 group. (B) Histograms displaying the quantitative data of CD4+, CD68+, CD20+, CD84+, CD86+, and CD206+ cells in the ADAR1-high and ADAR1- low groups. ADAR1+ (magenta), CD4+ T cells (CD4+, green), pan-macrophages (CD68+, yellow), CD8+ T cells (CD8+, red), B cells (CD20+, celeste), myeloid-derived suppressor cells (CD84+, white), M1 macrophages (CD86+, purple), and M2 macrophages (CD206+, orange). (mean ± SD, Student's t-test, ****p < 0.0001, ***p < 0.001, **p < 0.01, *p < 0.05, ns p > 0.05, not significant).

Article Snippet: After sequential application of ADAR1 (#81284, Cell Signaling Technology), CD4 (ab183685, Abcam), CD68 (#97778, Cell Signaling Technology) and CD8 (ab237709, Abcam) antibodies or CD20 (#48750, Cell Signaling Technology), CD84 (ab131256, Abcam), CD86 (#91882, Cell Signaling Technology), and CD206 (#24595, Cell Signaling Technology) antibodies to the sections, horseradish peroxidase- conjugated secondary antibody incubation nloaded from https://onlinelibrary.w iley.com /doi/10.1002/cam 4.6044 by G itam U niversity, W iley O nline L ibrary on [29/01/2024].

Techniques: Multiplex Assay, Immunohistochemistry, Staining, Derivative Assay